Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADAM protein family – its role in tumorigenesis, mechanisms of chemoresistance and potential as diagnostic and prognostic factors

1 Jan 2018

Abstract excerpt

ADAMs are a family of transmembrane proteins described for the first time in the 1990's. ADAMs is an abbreviation of "A Disintegrin and Metallo-proteinases". Their earliest known role was involvement in gamete fusion, and their adhesion properties in intercellular interactions also suggested involvement in tumor biology. Further research emphasized the importance of ADAM proteins in the regulation of neoplastic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to HER2/EGFR in Cancer Research
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30334448
DOI: 10.4149/neo_2018_171220n832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADAM protein family – its role in tumorigenesis, mechanisms of chemoresistance and potential as diagnostic and prognostic factorsPMID 30334448Read ↗

The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?Semantic proximity Read ↗

ADAMs in cancer cell proliferation and progressionSemantic proximity Read ↗

ADAMs and ADAMTSs in cancerSemantic proximity Read ↗

ADAM Proteins- Therapeutic Potential in CancerSemantic proximity Read ↗

ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistanceSemantic proximity Read ↗

ADAM9 as a Potential Target Molecule in CancerSemantic proximity Read ↗

An Overview of ADAM9: Structure, Activation, and Regulation in Human DiseasesSemantic proximity Read ↗

Active Metalloproteases of the A Disintegrin And Metalloprotease (ADAM) Family: Biological Function and StructureSemantic proximity Read ↗

ADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesisSemantic proximity Read ↗

Emerging roles of ADAM and ADAMTS metalloproteinases in cancerSemantic proximity Read ↗

Adamalysins in biology and diseaseSemantic proximity Read ↗

The roles of ADAMTS metalloproteinases in tumorigenesis and metastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.