Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

2 Oct 2018

Abstract excerpt

Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). We hypothesized that single nucleotide polymorphisms (SNPs) within the SP genes associate with CF or severity subgroups, either through single SNP or via SNP-SNP interactions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis Research Advances
Share to Neonatal Respiratory Health Research
Share to Pediatric health and respiratory diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30333828
DOI: 10.3389/fimmu.2018.02256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic FibrosisPMID 30333828Read ↗

Single Nucleotide Polymorphisms (SNP) and SNP-SNP Interactions of the Surfactant Protein Genes Are Associated With Idiopathic Pulmonary Fibrosis in a Mexican Study Group; Comparison With Hypersensitivity Pneumonitis.Semantic proximity Read ↗

Association of SNP-SNP interactions of surfactant protein genes with severity of respiratory syncytial virus infection in children.Semantic proximity Read ↗

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.Semantic proximity Read ↗

Surfactant proteins as genetic determinants of multifactorial pulmonary diseases.Semantic proximity Read ↗

Rare surfactant‐related variants in familial and sporadic pulmonary fibrosisSemantic proximity Read ↗

Functional polymorphisms in surfactant protein genes and chronic obstructive pulmonary disease risk: a meta-analysis.Semantic proximity Read ↗

Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.Semantic proximity Read ↗

Genetic Diversity of Human SP-A, a Molecule with Innate host Defense and Surfactant-Related Functions; Characteristics, Primary Function, and Significance.Semantic proximity Read ↗

Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms.Semantic proximity Read ↗

Association of surfactant protein B gene with chronic obstructive pulmonary disease susceptibility.Semantic proximity Read ↗

Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associationsSemantic proximity Read ↗

Linking surfactant proteins and genetic variants to COVID-19 severitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.