Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects Staphylococcus aureus from Killing by Host Phagocytes

15 Oct 2018

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA) poses a substantial threat to human health worldwide and evolves rapidly by acquiring mobile genetic elements, such as plasmids. Here we investigate how the copB - mco copper hypertolerance operon carried on a mobile genetic element contributes to the virulence potential of clinical isolates of MRSA. Copper is a key component of innate immune bactericidal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Trace Elements in Health
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30327441
DOI: 10.1128/mbio.00550-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects Staphylococcus aureus from Killing by Host PhagocytesPMID 30327441Read ↗

Mobile genetic element-encoded hypertolerance to copper protects <i>Staphylococcus aureus</i> from killing by host phagocytesSemantic proximity Read ↗

A horizontally gene transferred copper resistance locus confers hyper‐resistance to antibacterial copper toxicity and enables survival of community acquired methicillin resistant Staphylococcus aureus USA300 in macrophagesSemantic proximity Read ↗

The Staphylococcus aureus CsoR regulates both chromosomal and plasmid‐encoded copper resistance mechanismsSemantic proximity Read ↗

Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract InfectionSemantic proximity Read ↗

Copper as a central element critical to interkingdom interactions within a polymicrobial wound environmentSemantic proximity Read ↗

Geographic divergence of methicillin-resistant Staphylococcus aureus ST5-SCC mec I in the aftermath of a major earthquake and tsunami: impact of a plasmid harboring heavy metal resistance genesSemantic proximity Read ↗

Emergence of sequence type 779 methicillin-resistant Staphylococcus aureus harboring a novel pseudo staphylococcal cassette chromosome mec (SCCmec)-SCC-SCCCRISPR composite element in Irish hospitals.Semantic proximity Read ↗

Advances in Understanding of the Copper Homeostasis in Pseudomonas aeruginosaSemantic proximity Read ↗

Pathogenic adaptations to host-derived antibacterial copperSemantic proximity Read ↗

Adaptation of genetically monomorphic bacteria: evolution of copper resistance through multiple horizontal gene transfers of complex and versatile mobile genetic elements.Semantic proximity Read ↗

Stable antibiotic resistance and rapid human adaptation in livestock-associated MRSASemantic proximity Read ↗

Variability of SCCmec elements in livestock-associated CC398 MRSA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.