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Mobile genetic element-encoded hypertolerance to copper protects <i>Staphylococcus aureus</i> from killing by host phagocytes

2018-03-08

Abstract excerpt

Pathogens are exposed to toxic levels of copper during infection and copper tolerance may be a general virulence mechanism used by bacteria to resist host defences. In support of this, inactivation of copper-exporter genes has been found to reduce the virulence of bacterial pathogens in vivo . Here we investigate the role of copper-hypertolerance in methicillin resistant Staphylococcus aureus . We show that a co...

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Literature Corpus work
63d1c189-7354-5674-829d-7206c3297234
DOI
10.1101/279000
Open publication

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Mobile genetic element-encoded hypertolerance to copper protects <i>Staphylococcus aureus</i> from killing by host phagocytesDOI 10.1101/279000
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