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Stable antibiotic resistance and rapid human adaptation in livestock-associated MRSA

24 May 2022

Abstract excerpt

Mobile genetic elements (MGEs) are agents of horizontal gene transfer in bacteria, but can also be vertically inherited by daughter cells. Establishing the dynamics that led to contemporary patterns of MGEs in bacterial genomes is central to predicting the emergence and evolution of novel and resistant pathogens. Methicillin-resistant Staphylococcus aureus (MRSA) clonal-complex (CC) 398 is the dominant MRSA in...

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PMID: 35762208
DOI: 10.7554/elife.74819

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