Article
Capillary morphogenesis gene 2 maintains gastric cancer stem-like cell phenotype by activating a Wnt/β-catenin pathway.
Oncogene - 1 Jul 2018
Ji Chengdong, Yang Lang, Yi Weijing, Xiang Dongfang, Wang Yanxia, Zhou Zhihua, Qian Feng, Ren Yong, Cui Wei, Zhang Xia, Zhang Peng, Wang Ji Ming, Cui Youhong, Bian Xiuwu
Abstract excerpt
A growing body of evidence shows that the development and progression of gastric cancer (GC) is mainly associated to the presence of gastric cancer stem-like cells (GCSLCs). However, it is unclear how GCSLC population is maintained. This study aimed to explore the role of capillary morphogenesis gene 2 (CMG2) in GCSLC maintenance and the relevance to GC progression. We found that CMG2 was highly expressed in GC...
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