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Article

Cell adhesion-related gene somatic mutations are enriched in aggressive papillary thyroid microcarcinomas.

Journal of translational medicine - 1 Oct 2018

Song Jianlu, Wu Shouxin, Xia Xiaotian, Wang Yu, Fan Youben, Yang Zhili

Abstract excerpt

BACKGROUND: Approximately half of the documented increases in differentiated thyroid carcinoma is due to identification of papillary thyroid microcarcinomas (PTMCs). Knowing whether PTMC is aggressive is required for proper treatment, but until now, there has been no method for assessing these traits and understanding the underlying mechanisms for aggressiveness. METHODS: We performed whole-exome sequencing of 16...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30285776
DOI: 10.1186/s12967-018-1642-0
PMCID: PMC6167794

Genes

MUC5B
AEBP1
ALDH1L1
BRAF
CRNN
DCHS1
ITGA4
ITGA8
LAMC2
PCDHGA2
PPFIA1
RELN
ROCK1
TNN
VCAN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cell adhesion-related gene somatic mutations are enriched in aggressive papillary thyroid microcarcinomas.PMID 30285776Read ↗

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