Article
PTEN and TP53 Mutations in Oncocytic Follicular Carcinoma.
Endocrine pathology - 1 Dec 2015
Wei Shuanzeng, LiVolsi Virginia A, Montone Kathleen T, Morrissette Jennifer J D, Baloch Zubair W
Abstract excerpt
Oncocytic follicular carcinoma (OFC)/Hürthle cell carcinoma represents 3-4 % thyroid carcinomas and can be associated with more aggressive behavior and compromised survival compared to non-oncocytic thyroid carcinoma. In this study, we utilized targeted next-generation sequencing to investigate the molecular alterations in a heterogeneous group of clinically aggressive OFC. A total of 12 cases of OFC were...
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