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Article

GLI3 knockdown decreases stemness, cell proliferation and invasion in oral squamous cell carcinoma

26 Sept 2018

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is an extremely aggressive disease associated with a poor prognosis. Previous studies have established that cancer stem cells (CSCs) actively participate in OSCC development, progression and resistance to conventional treatments. Furthermore, CSCs frequently exhibit a deregulated expression of normal stem cell signalling pathways, thereby acquiring their distinctive abilities,...

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PMID: 30272273
DOI: 10.3892/ijo.2018.4572

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