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Article

Snail promotes metastasis of nasopharyngeal carcinoma partly by down‐regulating TEL2

25 Sept 2018

Abstract excerpt

BACKGROUND: Metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). We previously reported that TEL2, a negative regulator of SERPINE1, could inhibit NPC metastasis to lymph nodes. METHOD: A series of in vivo and in vitro assays were performed to elucidate the regulation between Snail and TEL2. TEL2 expression was analyzed in three representative NPC cell lines...

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Identifiers

PMID: 30253797
DOI: 10.1186/s40880-018-0328-6

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