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Article

Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway.

Journal of translational medicine - 27 Jan 2016

Zhao Xiao-Peng, Zhang Hong, Jiao Jiu-Yang, Tang Dong-Xiao, Wu Yu-Ling, Pan Chao-Bin

Abstract excerpt

BACKGROUND: Metastasis to long distance organs is the main reason leading to morality of tongue squamous cell carcinoma (TSCC); however, the molecular mechanisms are still unknown. High mobility group AT-hook 2 (HMGA2) is highly expressed in multiple metastatic carcinomas, in which it contributes to cancer progression, metastasis and poor prognosis by upregulating Snail expression and inducing epithelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26818837
DOI: 10.1186/s12967-016-0777-0
PMCID: PMC4730598

Genes

HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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