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Clinical, histopathological, and molecular features of IDH-wildtype indolent diffuse glioma: comparison with typical glioblastoma.

Journal of neuro-oncology - 1 Sept 2022

Suzuki Hayato, Ono Takahiro, Koyota Souichi, Takahashi Masataka, Sugai Tamotsu, Nanjo Hiroshi, Shimizu Hiroaki

Abstract excerpt

PURPOSE: IDH-wildtype (IDHwt) diffuse gliomas are treated as glioblastoma, however, some of these may show less aggressive clinical courses. The authors investigated the clinical, histopathological, and molecular characteristics of such IDHwt indolent diffuse gliomas (iDGwt), which have not been well documented in the literature. METHODS: Adult patients with IDHwt gliomas admitted between 2011 and 2020 were...

Topics

Adult
Brain Neoplasms
Glioblastoma
Glioma
Humans
Isocitrate Dehydrogenase
Kaplan-Meier Estimate
Mutation
Phosphatidylinositol 3-Kinases
Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35779193
DOI: 10.1007/s11060-022-04074-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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