Article
Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis.
Clinical epigenetics - 12 Sept 2018
Wang Min, Kong Weimin, He Biyu, Li Zhongqi, Song Huan, Shi Peiyi, Wang Jianming
Abstract excerpt
BACKGROUND: A variety of abnormalities in vitamin D metabolism have been reported in patients with active tuberculosis. However, intervention trials have produced inconsistent results. We hypothesized that genetic and epigenetic changes in the key genes of the vitamin D metabolic pathway may partly explain the differences between studies. METHODS: We performed a case-control study followed by a prospective cohort...
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