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Article

Human papillomavirus and genome instability: from productive infection to cancer

1 Jan 2018

Abstract excerpt

Infection with high oncogenic risk human papillomavirus types is the etiological factor of cervical cancer and a major cause of other epithelial malignancies, including vulvar, vaginal, anal, penile and head and neck carcinomas. These agents affect epithelial homeostasis through the expression of specific proteins that deregulate important cellular signaling pathways to achieve efficient viral replication. Among...

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PMID: 30208168
DOI: 10.6061/clinics/2018/e539s

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