Article
Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use
24 Jan 2025
Abstract excerpt
Human papillomaviruses, particularly high-risk human papillomaviruses, have been universally considered to be associated with the oncogenesis and progression of various cancers. The genome of human papillomaviruses is circular, double-stranded DNA that encodes early and late proteins. Each of the proteins is of crucial significance in infecting the epithelium of host cells persistently and supporting viral genome...
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