Article
Clinical and genetic backgrounds of hypertrophic cardiomyopathy with mid-ventricular obstruction.
Journal of human genetics - 1 Dec 2018
Inagaki Natsuko, Hayashi Takeharu, Takei Yasuyoshi, Tanimoto Kousuke, Chikamori Taishiro, Kimura Akinori
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left ventricular hypertrophy. This study aimed to reveal the clinical and genetic backgrounds of the unique HCM with mid-ventricular obstruction (HCM-MVO) subtype. We identified 34 patients with HCM-MVO in our cohort, and about half (47%) of these patients experienced adverse events. We analyzed 67 cardiomyopathy-associated genes in the patients....
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