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Article

A multidimensional impedance platform for the real-time analysis of single and combination drug pharmacology in patient-derived viable melanoma models.

Biosensors & bioelectronics - 1 Jan 2019

Seidel Diana, Rothe Rebecca, Kirsten Mandy, Jahnke Heinz-Georg, Dumann Konstantin, Ziemer Mirjana, Simon Jan-Christoph, Robitzki Andrea A

Abstract excerpt

In today's development of anticancer drugs, there is an enormous demand for sensitive, non-invasive real-time screening technologies to identify pharmacodynamics/-kinetics of single and combined drugs with high precision. The combination of sophisticated drug sensitivity testing with advanced in vitro tumor models reflecting heterogeneous tumor behavior in vivo is needed to more reasonably predict therapeutic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 30201332
DOI: 10.1016/j.bios.2018.08.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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