Article
SLC30A8 Gene rs13266634 C/T Polymorphism in Children with Type 1 Diabetes in Tamil Nadu, India
Journal of clinical research in pediatric endocrinology - 20 Feb 2019
Thirunavukkarasu Ramasamy, Asirvatham Arthur Joseph, Chitra Ayyappan, Jayalakshmi Mariakuttikan
Abstract excerpt
Objective: Zinc transporter 8 (ZnT8) is a multi-transmembrane protein situated in the insulin secretory granule of the islets of β-cells and is identified as a novel auto-antigen in type 1 diabetes (T1D). The gene coding for ZnT8, solute carrier family 30 member 8 (SLC30A8) is located on chromosome 8q24.11. This study aimed to identify the association of SLC30A8 rs13266634 C/T gene polymorphism with T1D in a...
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