Article
Traditional biomarkers in narcolepsy: experience of a Brazilian sleep centre.
Arquivos de neuro-psiquiatria - 1 Oct 2010
Coelho Fernando Morgadinho Santos, Pradella-Hallinan Márcia, Pedrazzoli Mario, Soares Carlos Augusto Senne, Fernandes Gustavo Bruniera Peres, Gonçalves André Leite, Tufik Sergio, Bittencourt Lia Rita Azeredo
Abstract excerpt
UNLABELLED: This study was thought to characterized clinical and laboratory findings of a narcoleptic patients in an out patients unit at São Paulo, Brazil. METHOD: 28 patients underwent polysomnographic recordings (PSG) and Multiple Sleep Latency Test (MSLT) were analyzed according to standard criteria. The analysis of HLADQB1*0602 allele was performed by PCR. The Hypocretin-1 in cerebral spinal fluid (CSF) was...
Topics
- Adult
- Aged
- Alleles
- Biomarkers
- Cataplexy
- Female
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Intracellular Signaling Peptides and Proteins
- Male
- Membrane Glycoproteins
- Middle Aged