Article
Expression profiling of ubiquitin-related genes in LKB1 mutant lung adenocarcinoma.
Scientific reports - 5 Sept 2018
Wang Guanghui, Bie Fenglong, Qu Xiao, Yang Xudong, Liu Shaorui, Wang Yu, Huang Cuicui, Wang Kai, Du Jiajun
Abstract excerpt
Liver kinase B1 (LKB1) is a tumor suppressor, and there is a very high proportion of LKB1 mutation in lung adenocarcinoma. The function of LKB1 is closely related to that of ubiquitin related genes. Our objective is to analyze the changes in ubiquitin-related genes in LKB1 mutant lung adenocarcinoma. We searched The Cancer Genome Atlas (TCGA) and obtained gene expression profiles from 230 lung adenocarcinoma...
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