Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors.

Acta neuropathologica communications - 31 Aug 2018

Ballester Leomar Y, Lu Guangrong, Zorofchian Soheil, Vantaku Venkatrao, Putluri Vasanta, Yan Yuanqing, Arevalo Octavio, Zhu Ping, Riascos Roy F, Sreekumar Arun, Esquenazi Yoshua, Putluri Nagireddy, Zhu Jay-Jiguang

Abstract excerpt

Cancer cells have altered cellular metabolism. Mutations in genes associated with key metabolic pathways (e.g., isocitrate dehydrogenase 1 and 2, IDH1/IDH2) are important drivers of cancer, including central nervous system (CNS) tumors. Therefore, we hypothesized that the abnormal metabolic state of CNS cancer cells leads to abnormal levels of metabolites in the CSF, and different CNS cancer types are associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Central Nervous System Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Imaging, Three-Dimensional

Share to Isocitrate Dehydrogenase

Share to Magnetic Resonance Imaging

Share to Metabolomics

Share to ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 30170631
DOI: 10.1186/s40478-018-0588-z
PMCID: PMC6117959

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors.PMID 30170631Read ↗

The genomic alterations in glioblastoma influence the levels of CSF metabolites.Semantic proximity Read ↗

Proteomic profiling of gliomas unveils immune and metabolism-driven subtypes with implications for anti-nucleotide metabolism therapySemantic proximity Read ↗

Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes.Semantic proximity Read ↗

Metabolomics of Glioma.Semantic proximity Read ↗

Multi-platform characterization of the human cerebrospinal fluid metabolome: a comprehensive and quantitative updateSemantic proximity Read ↗

Cerebrospinal fluid D-2-hydroxyglutarate for IDH-mutant glioma: utility for detection versus monitoringSemantic proximity Read ↗

Integrative Analysis of Metabolomic and Transcriptomic Data Reveals Metabolic Alterations in Glioma PatientsSemantic proximity Read ↗

Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging.Semantic proximity Read ↗

Distinct metabolic hallmarks of WHO classified adult glioma subtypes.Semantic proximity Read ↗

Proteomic landscape of primary and metastatic brain tumors for heterogeneity discovery.Semantic proximity Read ↗

Metabolomic profiles of human glioma inform patient survivalSemantic proximity Read ↗

Proteomic Profiling of Gliomas Unveils Immune and Metabolism-Driven Subtypes with Implications for Anti-Nucleotide Metabolism TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.