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Article

IL-1β and TNF-α regulate mouse amelotin gene transcription in gingival epithelial cells.

Journal of oral science - 23 Sept 2018

Noda Keisuke, Yamazaki Mizuho, Iwai Yasunobu, Matsui Sari, Kato Ayako, Takai Hideki, Nakayama Yohei, Ogata Yorimasa

Abstract excerpt

Amelotin (AMTN) is an enamel protein expressed in maturation-stage ameloblasts and junctional epithelium. To clarify the transcriptional regulation of the AMTN gene by interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), we conducted real-time PCR, Western blotting, transient transfection analyses with luciferase constructs including various lengths of the mouse AMTN gene promoter, and gel shift and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30158339
DOI: 10.2334/josnusd.17-0388

Genes

TNF
AMTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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