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Article

Haploid Screening for the Identification of Host Factors in Virus Infection.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Fessler Evelyn, Jae Lucas T

Abstract excerpt

Elucidating which host factors are exploited by viruses to infect target cells is key to our understanding of how these pathogens cause disease and how it might be counteracted by future therapies. Pooled gene-trap mutagenesis of haploid human HAP1 cells has proven to be a formidable tool for revealing genes involved in the infection process for a suite of human pathogenic viruses. This method has led to the...

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Source

Identifiers

PMID: 30151571
DOI: 10.1007/978-1-4939-8678-1_6

Genes

HAP1
NPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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