A novel DCL2-dependent miRNA pathway in tomato affects susceptibility to RNA viruses.

doi:10.1101/gad.313601.118

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Article

A novel DCL2-dependent miRNA pathway in tomato affects susceptibility to RNA viruses.

Genes & development - 1 Sept 2018

Wang Zhengming, Hardcastle Thomas J, Canto Pastor Alex, Yip Wing Hin, Tang Shuoya, Baulcombe David C

Abstract excerpt

Tomato Dicer-like2 (slDCL2) is a key component of resistance pathways against potato virus X (PVX) and tobacco mosaic virus (TMV). It is also required for production of endogenous small RNAs, including miR6026 and other noncanonical microRNAs (miRNAs). The slDCL2 mRNAs are targets of these slDCL2-dependent RNAs in a feedback loop that was disrupted by target mimic RNAs of miR6026. In lines expressing these RNAs,...

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PMID: 30150254
DOI: 10.1101/gad.313601.118
PMCID: PMC6120711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.