Phenotypic alteration of basal cells in oral lichen planus; switching keratin 19 and desmoglein 1 expression.

doi:10.2334/josnusd.17-0396

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Article

Phenotypic alteration of basal cells in oral lichen planus; switching keratin 19 and desmoglein 1 expression.

Journal of oral science - 27 Dec 2018

Shimada Katsumitsu, Ochiai Takanaga, Shen Fa-Chih, Hasegawa Hiromasa

Abstract excerpt

In oral lichen planus, extracellular matrix and basal cells are damaged by T-lymphocytes. As a consequence, changes in expression of collagen fibers within the connective tissue and cytoskeletons of the epithelial tissue can be observed. With the goal of examining the characteristic changes undergone by basal cells as a consequence of T-lymphocytes damage in oral lichen planus, we investigated protein expression...

Topics

Case-Control Studies
Collagen
Desmoglein 1
Epithelial Cells
Humans
Immunohistochemistry
Keratin-19
Ki-67 Antigen
Lichen Planus, Oral
Middle Aged
Phenotype

Source

Open in PubMed

Identifiers

PMID: 30146538
DOI: 10.2334/josnusd.17-0396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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