Article
An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Apr 2008
Lalli Anand, Tilakaratne Wanninayake M, Ariyawardana Anura, Fitchett Caroline, Leigh Irene M, Hagi-Pavli Eleni, Cruchley Alan T, Parkinson E Kenneth, Teh Muy-Teck, Fortune Farida, Waseem Ahmad
Abstract excerpt
Oral submucous fibrosis (OSF) is characterized by abnormal collagen metabolism in the submucosal connective tissue. Its influence on the overlying epithelium is not known but about 14% of OSF cases undergo malignant transformation to squamous cell carcinoma indicating association with abnormality of the epithelium. Here, we have defined the keratin expression profile, by immunohistochemistry and quantitative...
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