Article
Generation of trichogenic adipose-derived stem cells by expression of three factors.
Journal of dermatological science - 1 Oct 2018
Choi Nahyun, Choi Junjeong, Kim Ji Hye, Jang Yaeji, Yeo Joo Hye, Kang Juwon, Song Seung Yong, Lee Jinu, Sung Jong-Hyuk
Abstract excerpt
BACKGROUND: Previous studies demonstrated that adipose-derived stem cells (ASCs) can promote hair growth, but unmet needs exist for enhancing ASC hair inductivity. OBJECTIVE: Therefore, we introduced three trichogenic factors platelet-derived growth factor-A, SOX2, and β-catenin to ASCs (tfASCs) and evaluated whether tfASCs have similar characteristics as dermal papilla (DP) cells. METHOD: Global gene expression...
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