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Article

Physical exercise contributes to cisplatin-induced nephrotoxicity protection with decreased CD4+ T cells activation.

Molecular immunology - 1 Sept 2018

Miyagi Mariana Yasue Saito, Latancia Marcela Teatin, Testagrossa Leonardo Abreu, Andrade-Oliveira Vinicius de, Pereira Welbert Oliveira, Hiyane Meire Ioshie, Enjiu Lucas Maceratesi, Pisciottano Marcus, Seelaender Marilia Cerqueira Leite, Camara Niels Olsen Saraiva, Amano Mariane Tami

Abstract excerpt

Cisplatin is a chemotherapy used to treat different types of cancer, such as testicular, bladder and head and neck. Physical exercise has been shown to improve cancer therapy and recently, it was demonstrated to be able to diminish side effects such as acute kidney injury (AKI), a common side effect in cisplatin treatment. In both cases, the modulation of inflammatory cytokines seems to be one of the mechanisms,...

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Identifiers

PMID: 30144701
DOI: 10.1016/j.molimm.2018.08.014

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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