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Article

Detection of Variants in Patients with Idiopathic Ventricular Fibrillation by Whole-exome Sequencing.

Annals of clinical and laboratory science - 1 Jul 2018

Chang Ya-Sian, Lee Chien-Chin, Huang Hsi-Yuan, Lin Kuo-Hung, Chen Jan-Yow, Chang Kuan-Cheng, Chang Jan-Gowth

Abstract excerpt

AIMS AND BACKGROUND: Idiopathic ventricular fibrillation (IVF) is a cause of sudden cardiac death (SCD). The frequency of mutations in disease-causing genes ranges, on average, between 16 and 48% in SCD cases. This study aimed to identify novel mutations in IVF patients without KCNQ1, KCNH2, and SCN5A mutations using whole-exome sequencing (WES). METHODS: Genomic DNA extracted from peripheral blood samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30143482

Genes

KCNH2
KCNQ1
SCD
MYPN
TCAP
TNNT2
TTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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