Article
The genetics underlying idiopathic ventricular fibrillation: A special role for catecholaminergic polymorphic ventricular tachycardia?
International journal of cardiology - 1 Jan 2018
Leinonen Jaakko T, Crotti Lia, Djupsjöbacka Aurora, Castelletti Silvia, Junna Nella, Ghidoni Alice, Tuiskula Annukka M, Spazzolini Carla, Dagradi Federica, Viitasalo Matti, Kontula Kimmo, Kotta Maria-Christina, Widén Elisabeth, Swan Heikki, Schwartz Peter J
Abstract excerpt
BACKGROUND: Ventricular fibrillation (VF) is a major cause of sudden cardiac death. In some cases clinical investigations fail to identify the underlying cause and the event is classified as idiopathic (IVF). Since mutations in arrhythmia-associated genes frequently determine arrhythmia susceptibility, screening for disease-predisposing variants could improve IVF diagnostics. METHODS AND RESULTS: The study...
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