Article
The role of triiodothyronine hormone and mechanically-stressed endothelial cell paracrine signalling synergism in gene reprogramming during hBMSC-stimulated osteogenic phenotype in vitro.
Molecular and cellular endocrinology - 15 Dec 2018
da Silva Rodrigo A, de Camargo Andrade Amanda Fantini, da Silva Feltran Geórgia, Fernandes Célio Júnior da C, de Assis Rahyza Inacio F, Ferreira Marcel Rodrigues, Andia Denise C, Zambuzzi Willian F
Abstract excerpt
We therefore investigated whether there is synergism between triiodothyronine (T3) hormone and trophic molecules released from mechanically-stressed endothelial cells (EC-enriched medium) in osteogenic phenotype by mapping classical repertory of genes. Although there are studies reporting the efficiency of T3 hormone on bone cells, it is scarce considering their effect in conjunction with other physiologically...
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