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Article

Reversine promotes browning of white adipocytes by suppressing miR-133a.

Journal of cellular physiology - 1 Apr 2019

Kim Saetbyul, Park Jong Woo, Lee Min Gyu, Nam Ki Hong, Park Jee Hun, Oh Hwamok, Lee Jieun, Han Jihoon, Yi Sang Ah, Han Jeung-Whan

Abstract excerpt

Brown adipocytes are characterized by a high number of uncoupling protein 1 (UCP1)-positive mitochondrial content and increased thermogenic capacity. As UCP1-enriched cells can consume lipids by generating heat, browning of white adipocytes is now highlighted as a promising approach for the prevention of obesity and obesity-associated metabolic diseases. Upon cold exposure or β-adrenergic stimuli, downregulation...

Read the complete abstract on PubMed

Topics

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Share to 3T3-L1 Cells
Share to Adipose Tissue, Brown

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, High-Fat

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Source

Identifiers

PMID: 30132867
DOI: 10.1002/jcp.27148

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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