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Article

The disrupted balance between hair follicles and sebaceous glands in Hoxc13-ablated rabbits.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2019

Deng Jichao, Chen Mao, Liu Zhiquan, Song Yuning, Sui Tingting, Lai Liangxue, Li Zhanjun

Abstract excerpt

Pure hair and nail ectodermal dysplasia 9 (ECTD-9) is an autosomal recessive genetic disease caused by mutation of HOXC13 and is characterized by hypotrichosis and nail dystrophy in humans. Unlike patients with ECTD-9, Hoxc13-mutated mice and pigs do not faithfully recapitulate the phenotype of hypotrichosis, so there is a limited understanding of the molecular mechanism of Hoxc13-mediated hypotrichosis in animal...

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Identifiers

PMID: 30125135
DOI: 10.1096/fj.201800928RR

Genes

HOXC13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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