Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developments in anti-complement therapy; from disease to clinical trial

16 Aug 2018

Abstract excerpt

The complement system is well known for its role in innate immunity and in maintenance of tissue homeostasis, providing a first line of defence against infection and playing a key role in flagging apoptotic cells and debris for disposal. Unfortunately complement also contributes to pathogenesis of a number of diseases; in some cases driving pathology, and in others amplifying or exacerbating the inflammatory and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Mosquito-borne diseases and control
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30121124
DOI: 10.1016/j.molimm.2018.06.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developments in anti-complement therapy; from disease to clinical trialPMID 30121124Read ↗

Complement‐targeted therapeutics: Are we there yet, or just getting started?Semantic proximity Read ↗

Complement‐targeted therapeutics: An emerging field enabled by academic drug discoverySemantic proximity Read ↗

Complement in therapy and diseaseSemantic proximity Read ↗

Complement in human disease: approved and up-and-coming therapeuticsSemantic proximity Read ↗

Review: The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune DiseasesSemantic proximity Read ↗

The alternative pathway of complement in disease: opportunities for therapeutic targetingSemantic proximity Read ↗

Expansion of Anticomplement Therapy Indications from Rare Genetic Disorders to Common Kidney Diseases.Semantic proximity Read ↗

Therapeutic targeting of the complement systemSemantic proximity Read ↗

Therapeutic Lessons to be Learned From the Role of Complement Regulators as Double-Edged Sword in Health and DiseaseSemantic proximity Read ↗

Complement in Immune and Inflammatory Disorders: Therapeutic InterventionsSemantic proximity Read ↗

Complement inhibitors: a resurgent concept in anti-inflammatory therapeuticsSemantic proximity Read ↗

Therapeutic targeting of the complement system in ocular diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.