Expansion of Anticomplement Therapy Indications from Rare Genetic Disorders to Common Kidney Diseases.

Abstract excerpt

Complement constitutes a major part of the innate immune system. The study of complement in human health has historically focused on infection risks associated with complement protein deficiencies; however, recent interest in the field has focused on overactivation of complement as a cause of immune injury and the development of anticomplement therapies to treat human diseases. The kidneys are particularly...

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