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Article

A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression

15 Aug 2018

Abstract excerpt

Genomic and transcriptome sequencing of bladder cancer (BLCA) has identified multiple molecular alterations during cancer progression. Many of these identified genetic and epigenetic changes play a role in the progression of this disease. Studies have identified molecular subtypes in muscle-invasive bladder cancer (MIBC) with different sensitivities to frontline therapy suggesting the heterogeneity in these...

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Share to Adenosine and Purinergic Signaling
Share to Bladder and Urothelial Cancer Treatments
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PMID: 30121007
DOI: 10.1016/j.neo.2018.07.006

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