Self-Digestion for Lifespan Extension: Enhanced Autophagy Delays Aging.

doi:10.1016/j.molcel.2018.08.002

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Article

Self-Digestion for Lifespan Extension: Enhanced Autophagy Delays Aging.

Molecular cell - 16 Aug 2018

Arensman Michael D, Eng Christina H

Abstract excerpt

By systemically boosting autophagy with a knockin mutation that prevents binding of beclin 1 to BCL2, Fernández et al. (2018) demonstrate that enhanced autophagy prolongs lifespan in mammals.

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Identifiers

PMID: 30118677
DOI: 10.1016/j.molcel.2018.08.002

Genes

BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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