Article
Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1.
International journal of molecular sciences - 16 Aug 2018
Hsu Ya-Ling, Chen Yi-Jen, Chang Wei-An, Jian Shu-Fang, Fan Hsiao-Li, Wang Jaw-Yuan, Kuo Po-Lin
Abstract excerpt
Crosstalk of a tumor with its microenvironment is a critical factor contributing to cancer development. This study investigates the soluble factors released by tumor-associated dendritic cells (TADCs) responsible for increasing cancer stem cell (CSC) properties, cell mobility, and epithelial-to-mesenchymal transition (EMT). Dendritic cells (DCs) of colon cancer patients were collected for phenotype and CXCL1...
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