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Article

BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer.

British journal of cancer - 1 Sept 2018

Tsibulak Irina, Wieser Verena, Degasper Christine, Shivalingaiah Giridhar, Wenzel Sören, Sprung Susanne, Lax Sigurd F, Marth Christian, Fiegl Heidelinde, Zeimet Alain G

Abstract excerpt

BACKGROUND: Mutations in BRCA1 and BRCA2 are associated with better survival in ovarian cancer (OC) patients due to a better response to platinum-based chemotherapy. However, the impact of the BRCA1/2 mRNA-expression is not well characterized in OC. PATIENTS AND METHODS: We investigated BRCA1/2 mRNA-expression in 12 non-neoplastic fallopian tubes and 201 epithelial OCs in relation to their clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30111871
DOI: 10.1038/s41416-018-0217-4
PMCID: PMC6173779

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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