Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic heterogeneity and mutational signature in Chinese Epstein-Barr virus-positive diffuse large B-cell lymphoma.

PloS one - 1 Jan 2018

Liu Fang, Wang Zhe, Zhou Xiaoge, Liu Qing, Chen Gang, Xiao Hualiang, Yin Weihua, Nakamura Shigeo, Rao Huilan

Abstract excerpt

Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (EBV+ DLBCL) is typically an aggressive tumor in elderly patients. However, in a subset of young patients, EBV+ DLBCL follows a relatively indolent clinical course and exhibits a good response to chemotherapy. This lymphoma comprises polymorphous lymphoma and large cell lymphomas subtypes, with the latter subtype showing a significantly poorer...

Topics

Join the communities discussing this publication.

Aged
Asian People
Epstein-Barr Virus Infections
Exome Sequencing
Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Heterogeneity

Lymphoma, Large B-Cell, Diffuse

Source

Open in PubMed Open full text

Identifiers

PMID: 30106962
DOI: 10.1371/journal.pone.0201546
PMCID: PMC6091946

Genes

FADS6
LNP1
PRSS3
TRAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic heterogeneity and mutational signature in Chinese Epstein-Barr virus-positive diffuse large B-cell lymphoma.PMID 30106962Read ↗

Genetic heterogeneity of diffuse large B-cell lymphoma.Semantic proximity Read ↗

Molecular profiling of EBV associated diffuse large B-cell lymphoma.Semantic proximity Read ↗

Genomic insights into the pathogenesis of Epstein-Barr virus-associated diffuse large B-cell lymphoma by whole-genome and targeted amplicon sequencing.Semantic proximity Read ↗

Integrating Epstein-Barr virus (EBV) status into diffuse large B cell lymphoma (DLBCL) geneticsSemantic proximity Read ↗

Genetic heterogeneity of DLBCL, not otherwise specified.Semantic proximity Read ↗

Association of Epstein-Barr virus genomic alterations with human pathologiesSemantic proximity Read ↗

Genomic Mutation Profile of Primary Gastrointestinal Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Distinct subtype distribution and somatic mutation spectrum of lymphomas in East Asia.Semantic proximity Read ↗

Comprehensive Genomic Profiling of EBV-Positive Diffuse Large B-cell Lymphoma and the Expression and Clinicopathological Correlations of Some Related GenesSemantic proximity Read ↗

Next generation sequencing and the management of diffuse large B-cell lymphoma: from whole exome analysis to targeted therapy.Semantic proximity Read ↗

Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphomaSemantic proximity Read ↗

Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.