Pigmentation phototype and prostate and breast cancer in a select Spanish population-A Mendelian randomization analysis in the MCC-Spain study.

doi:10.1371/journal.pone.0201750

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Article

Pigmentation phototype and prostate and breast cancer in a select Spanish population-A Mendelian randomization analysis in the MCC-Spain study.

PloS one - 1 Jan 2018

Gómez-Acebo Inés, Dierssen-Sotos Trinidad, Palazuelos Camilo, Fernández-Navarro Pablo, Castaño-Vinyals Gemma, Alonso-Molero Jéssica, Urtiaga Carmen, Fernández-Villa Tania, Ardanaz Eva, Rivas-Del-Fresno Manuel, Molina-Barceló Ana, Jiménez-Moleón José-Juan, García-Martinez Lidia, Amiano Pilar, Rodriguez-Cundin Paz, Moreno Víctor, Pérez-Gómez Beatriz, Aragonés Nuria, Kogevinas Manolis, Pollán Marina, Llorca Javier

Abstract excerpt

INTRODUCTION: Phototype has been associated with an increased risk of prostate cancer, and it is yet unknown if it is related to other hormone-dependent cancers, such as breast cancer or whether this association could be considered causal. METHODS: We examined the association between the phototype and breast and prostate cancers using a Mendelian randomization analysis. We studied 1,738 incident cases of breast...

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PMID: 30106959
DOI: 10.1371/journal.pone.0201750
PMCID: PMC6091948

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