Article
Identification of novel immune-relevant drug target genes for Alzheimer's Disease by combining ontology inference with network analysis.
CNS neuroscience & therapeutics - 1 Dec 2018
Han Zhi-Jie, Xue Wei-Wei, Tao Lin, Zhu Feng
Abstract excerpt
AIMS: Alzheimer's disease (AD) is one of the leading causes of death in elderly people. Its pathogenesis is greatly associated with the abnormality of immune system. However, only a few immune-relevant AD drug target genes have been discovered up to now, and it is speculated that there are still many potential drug target genes of AD (at least immune-relevant genes) to be discovered. Thus, this study was designed...
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