Article
Replication-independent reduction in the number and diversity of recombinant progeny viruses in chickens vaccinated with an attenuated infectious laryngotracheitis vaccine.
Vaccine - 11 Sept 2018
Loncoman Carlos A, Hartley Carol A, Coppo Mauricio J C, Browning Glenn F, Quinteros José A, Diaz-Méndez Andrés, Thilakarathne Dulari, Fakhri Omid, Vaz Paola K, Devlin Joanne M
Abstract excerpt
Recombination is closely linked with virus replication and is an important mechanism that contributes to genome diversification and evolution in alphaherpesviruses. Infectious laryngotracheitis (ILTV; Gallid alphaherpesvirus 1) is an alphaherpesvirus that causes respiratory disease in poultry. In the past, natural (field) recombination events between different strains of ILTV generated virulent recombinant...
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