Article
Genetic and platelet function testing of antiplatelet therapy for percutaneous coronary intervention: the ARCTIC-GENE study.
European journal of clinical pharmacology - 1 Nov 2015
Collet Jean-Philippe, Hulot Jean-Sébastien, Cuisset Thomas, Rangé Grégoire, Cayla Guillaume, Van Belle Eric, Elhadad Simon, Rousseau Hélène, Sabouret Pierre, O'Connor Stephen A, Abtan Jérémie, Kerneis Mathieu, Saint-Etienne Christophe, Barthélémy Olivier, Beygui Farzin, Silvain Johanne, Vicaut Eric, Montalescot Gilles
Abstract excerpt
BACKGROUND: The ARCTIC study randomized 2440 patients scheduled for stent implantation to a strategy of platelet function monitoring with drug adjustment in patients who had a poor response to antiplatelet therapy or to a conventional strategy without monitoring and drug adjustment. No significant improvement in clinical outcomes with platelet function monitoring was observed. OBJECTIVE: The purpose of this study...
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