Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa Toxicity to Spodoptera frugiperda by Domain III Mutations Indicates There Are Two Limiting Steps in Toxicity as Defined by Receptor Binding and Protein Stability.

doi:10.1128/AEM.01393-18

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Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa Toxicity to Spodoptera frugiperda by Domain III Mutations Indicates There Are Two Limiting Steps in Toxicity as Defined by Receptor Binding and Protein Stability.

Applied and environmental microbiology - 15 Oct 2018

Gómez Isabel, Ocelotl Josue, Sánchez Jorge, Lima Christina, Martins Erica, Rosales-Juárez Anayeli, Aguilar-Medel Sotero, Abad André, Dong Hua, Monnerat Rose, Peña Guadalupe, Zhang Jie, Nelson Mark, Wu Gusui, Bravo Alejandra, Soberón Mario

Abstract excerpt

Bacillus thuringiensis Cry1Ab and Cry1Fa toxins are environmentally safe insecticides that control important insect pests. Spodoptera frugiperda is an important maize pest that shows low susceptibility to Cry1A toxins, in contrast to Cry1Fa, which is highly active against this pest and is used in transgenic maize for S. frugiperda control. The β16 region from domain III of Cry1Ab has been shown to be involved in...

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PMID: 30097439
DOI: 10.1128/AEM.01393-18
PMCID: PMC6182889

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Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa Toxicity to Spodoptera frugiperda by Domain III Mutations Indicates There Are Two Limiting Steps in Toxicity as Defined by Receptor Binding and Protein Stability.PMID 30097439Read ↗

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