Article
TNIP1/ANXA6 and CSMD1 variants interacting with cigarette smoking, alcohol intake affect risk of psoriasis.
Journal of dermatological science - 1 May 2013
Yin Xian-yong, Cheng Hui, Wang Wen-ju, Wang Wen-jun, Fu Hong-yang, Liu Ling-hua, Zhang Feng-yu, Yang Sen, Zhang Xue-jun
Abstract excerpt
BACKGROUND: Psoriasis is a common multi-factorial skin disease, in which gene-gene and gene-environment interactions may affect the onset, manifestation and clinical course. OBJECTIVE: To investigate the underlying gene-environment interaction among several established susceptibility genes, cigarette smoking and alcohol intake. METHODS: Using a two-stage case-control design, we searched for pairwise interactions...
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