Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hedgehog Signaling Pathway and Autophagy in Cancer

3 Aug 2018

Abstract excerpt

Hedgehog (Hh) pathway controls complex developmental processes in vertebrates. Abnormal activation of Hh pathway is responsible for tumorigenesis and maintenance of multiple cancers, and thus addressing this represents promising therapeutic opportunities. In recent years, two Hh inhibitors have been approved for basal cell carcinoma (BCC) treatment and show extraordinary clinical outcomes. Meanwhile, a series of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hedgehog Signaling Pathway Studies
Share to Oral and Maxillofacial Pathology
Share to Tumors and Oncological Cases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30081498
DOI: 10.3390/ijms19082279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hedgehog Signaling Pathway and Autophagy in CancerPMID 30081498Read ↗

Regulating autophagy facilitated therapeutic efficacy of the sonic Hedgehog pathway inhibition on lung adenocarcinoma through GLI2 suppression and ROS productionSemantic proximity Read ↗

The Interaction Between Autophagy and JAK/STAT3 Signaling Pathway in TumorsSemantic proximity Read ↗

Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemiaSemantic proximity Read ↗

Role of autophagy in head and neck cancer and therapeutic resistanceSemantic proximity Read ↗

The Role of Autophagy in Liver Cancer: Crosstalk in Signaling Pathways and Potential Therapeutic TargetsSemantic proximity Read ↗

The Hedgehog signalling pathway regulates autophagySemantic proximity Read ↗

Unravelling the multifaceted roles of Atg proteins to improve cancer therapySemantic proximity Read ↗

Autophagy awakens—the myriad roles of autophagy in head and neck cancer development and therapeutic responseSemantic proximity Read ↗

Hedgehog pathway and cancer: A new area (Review).Semantic proximity Read ↗

Cross talk between autophagy and oncogenic signaling pathways and implications for cancer therapySemantic proximity Read ↗

The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectivesSemantic proximity Read ↗

The Utility of Hedgehog Signaling Pathway Inhibition for CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.