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Article

Immune response and within-host viral evolution: Immune response can accelerate evolution.

Journal of theoretical biology - 7 Nov 2018

Korobeinikov Andrei

Abstract excerpt

The objectives of this paper are to explore the impact of immune response on within-host viral evolution towards higher Darwinian fitness and, in particular, to verify a hypothesis that immune response, which is insufficient to annihilate a viral infection, can accelerate this evolution. To address this issue, a model of within-host viral evolution with immune response is formulated. This model is an extension of...

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Identifiers

PMID: 30081004
DOI: 10.1016/j.jtbi.2018.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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