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Multiple Classes of Antiviral Agents Exhibit In Vitro Activity against Human Rhinovirus Type C

24 Dec 2013

Abstract excerpt

Human rhinovirus type C (HRV-C) is a newly discovered enterovirus species frequently associated with exacerbation of asthma and other acute respiratory conditions. Until recently, HRV-C could not be propagated in vitro, hampering in-depth characterization of the virus replication cycle and preventing efficient testing of antiviral agents. Herein we describe several subgenomic RNA replicon systems and a cell...

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PMID: 24366736
DOI: 10.1128/aac.01746-13

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