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Article

Rhinovirus C targets ciliated airway epithelial cells

4 May 2017

Abstract excerpt

BACKGROUND: The Rhinovirus C (RV-C), first identified in 2006, produce high symptom burdens in children and asthmatics, however, their primary target host cell in the airways remains unknown. Our primary hypotheses were that RV-C target ciliated airway epithelial cells (AECs), and that cell specificity is determined by restricted and high expression of the only known RV-C cell-entry factor, cadherin related...

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PMID: 28472984
DOI: 10.1186/s12931-017-0567-0

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